Parker Ackley considered the .220 Swift to be the best deer cartridge that he had tried, and he had tried a lot. Yes at 225 yards other cartridges would work nearly as well with less powder etc, but a .220 Swift would have to be one of the most fun. It would also be very interesting to fully explore the very high velocity/small projectile theory fully. The only difference I would make to the classic 14 twist Swift is to go 12 twist so as to use the 53 grain Vmax as it's bc is higher than most other projectiles around that weight, and the 12 twist opens a few more doors for the all-copper bullets around 50 grains.