I did it with an -06 years and years ago. My uncle was convinced they were better "brush busters" than anything else out there.
I do know that round nosers seem to whack them pretty hard. They even sound different on impact... Its a deeper pitched 'THWOCK' than you get with spitzers.
Oh, it kills big Muleys and Whiteys just fine. Never got around to trying them on Elk and Bears.
Also, it seemed in my limited sample of 10 or so critters that there was less bloodshot meat, if thats a concern.
Here in Montana, I hunt Elk and Bears with good Ol' Schoo' 165 grain Partitions
