I don't see why it wouldn't work, as stated in this thread bullet placement and bullet construction is more important that case capacity.
I started elk hunting in 1975 with a 270 Win. loaded w/ 150 Gr. NPT and it worked a few times with no issues. My uncle used his 257 Roberts from the late 1950's until around 2000 shooting factory ammo for deer and elk and he only needed a follow up shot once in all those years.
If I lived in elk country I'd haul my Tikka T3 Hunter 6.5x55 mm up the mountain loaded w/ 140 Gr. NAB or PT (whichever shot best) and make sure my knives are sharp.
StarchedCover
