Not MD but the grooves greatly reduce pressure due to less bearing surface and less swagging pressure. The Barnes produce even lower pressures than some comparable C&C bullets. The E-Tips and GMX will produce more pressure to the point that maximum loads need to be cut back, some times as much as a grain and a half. The respective velocities also follow suit. Not a huge difference and many shooters ignore it and get away with it.
The hollow base mono produces extreme expansion while not shedding petals. I have not tried them yet. Have some Lehighs ready to go but have not shot any game with them yet. I will have to try them on my favorite test medium, feral hogs soon. The Cutting Edge bullets have a good reputation but have yet to try them, likewise with Hammer bullets. Too many good bullets, not enough time.
I always wonder what the TSX, TTSX, & LRX would do if Barnes used their old blue coating on them? I only shot a couple boxes of the Blue Meanies but they seemed to live up to their claims, more velocity and less fouling.