I haven’t played with the E-Tip’s at all, usually when I buy Noslers it’s Partitions or AccuBonds. But I have shot my fair share of TSX & TTSX in a variety of calibers. I also been loading quite a few GMX in a variety of calibers. Not much different on game performance that I have noticed, the GMX may be a tad easier to find a load for, seating depth is not quite as finicky as Barnes.(slightly) The only other difference is barrel fouling maybe more noticeable with the Barnes , barrel dependant and not a big deal in hunting situations. I went on a five year run where all I used were mono-metal bullets, and now I’m back to shooting a mix of C&C, Bonded, & Monos. Currently on the hunt for 90 gr GMX in 6mm hoping they shoot close to current 90 gr load for some testing.