If you cast your own, and have the ability to source two pots, I would highly recommend a heat treated base (WW alloy) with the combination of a pure lead hollow point or plain lead softnose
I made some for a friend in 45 Super (rifle) and he proceeded to shoot three deer that I gutted and butchered without a single bullet recovered. Wound diameter resembled 50 cent pieces.
They were 238 gr. hollow points driven at 1,800 fps, Lyman 452423 type.
I would wager a soft nosed, heat treated cast bullet would easily outperform the Sierra, provided the slug fits.
