Whichever one has back-up open sights.

I run 225 grain interbonds or 225 grain fusions for winter caribou or in the mountains. These are wide-expanding bullets that have greater killing effect on lighter skin game at longer range.

If i take a sheep, hike out is with the scope dropped, and the gun stoked with 275 grain a-frame handloads sighted to the open sights for the hike out. For that occasional bear that might challenge you for your pack full o bloody sheep meat.

That is the versatility of the 338-06/338rcm ballistics. A great mountain rifle cartridge in big bear country. But ive been saying this since 2008.