In my experience, the Barnes really needs speed to wreck lungs well. I shot them in 223AI at 3,300 or so and they worked fine on deer and hogs, although I only shot them inside 150yds or so. Little buzz-saws at that speed. Lung hits were actually okay on blood trails. Not amazing, but fairly okay. I shot a coyote at 200-250yds with the same bullet from an AR carbine and it was not impressive at the lower impact speed. He needed several body hits to go down.
I think the bigger-cased, high-RPM .22 centerfires make the most of the 60-70gr mono bullets, as they have the horsepower to make them perform. Your standard 18-22" .223 bolt gun or AR is better off with a softer bullet if you want to shoot 60-75gr, and if you want to go with a mono, I'd look at a 50-55gr version to keep the speed up. I believe that several posters here on this thread feel the same way.
