A 'smith that I think highly of laughs at the folks who say a 22-250 isn't a good deer rifle, but he laughs equally at the quick twist .224" guys, since he and his brother have been killing deer in CO and NM for over 50 years with 1 in 14" ROT 22-250s and 55 grain varmint bullets.
Knowing how to, when to, and when NOT to shoot are, in his opinion, more important than the cartridge/bullet combination. He may be old-fashion, but old-fashion seems to have worked pretty well down there in SW CO.
