It’s safe to say they are both up to killing game way out there. Question would be, is the shooter. When the 260 Rem was introduced it was hailed as a 270 Win in ballistics with less recoil and better bullets. The 6.5 Creedmoor is an improvement over the 260 by way of faster twist, in most cases, and able to handle longer projectiles by way of better case design. If it were me I would take the 6.5 CM and never look back.