There are calibres which could well die without me being affected in the slightest. Quite a number of them really. However I'd actually be reluctant to push for any to be dropped because no doubt there'd be someone, somewhere, who'd be adversely affected. I have been affected by calibres becoming "no longer commercially available" myself, and it can be quite a PITA to chase brass (or modify it) and sometimes bullets for these orphans.

Of course it is in the interests of the big makers to keep coming out with new calibres and at the same time to render obsolete the less popular ones. That way they can expect that you'll just have to keep buying new guns, dies etc. I am glad that there are specialists who make some of the less-common stuff, to keep the older and perhaps more obscure guns going. .