While I hate to disagree with mule deer but I’ve had an older 150 grain Nosler ballistic tip hit and fragment on a bull elks ribs. It died after roughly 500 yards luckily leaving a bloody trail in the snow the whole way. Had a hunting partners bull elk shot through both lungs & broken shoulder walking steadily toward the private ranch before I finished it with a too high spine shot. They aren’t bulletproof but they are tough & sometimes can cover ground with clearly fatal wounds.