Not exactly an -06, but my go-to PG rifle in Africa has been a light 300WSM, always handloaded with Nosler 180 grain PT Partitions. It’s been effective on PG from steinbok to eland from 40-200 yds.
I would anticipate the same performance from a 180 Partition fired from an -06. In my case it just happens that my Old Reliable has been an -06 cousin, a 300 WSM!! 😊