My only "experience" was in Newfoundland a couple of years ago. Two different guys in camp, both using ELDX's in 30 cal, 1 in a .308 and the other .30-06. I think they were 178's???
The guy with the .308 shot a caribou at about 60 yards, quartering away. The bullet made it to the 1st lung. It ran a long ways before dropping. The bullet was in pieces. Horrible penetration. I saw the bullet pieces.
The guy with the .30-06 shot a nice bull moose at about the same distance, broadside. According to the guide, the first shot was well placed in the lungs. He had enough time to empty his gun and get into his pack for more ammo, before it dropped. None of the other bullets were placed very well after the bull started moving. Later examination showed the first bullet barely made it into the first lung and was in many pieces. I saw the pieces. I'll never use that bullet.

Ready to get flamed.