I'd say to use them like you are shooting an SST or old-school 1980's-1990's NBT. My limited experience with them at sub-2700fps impact velocity has shown them to not be serious penetrator. They are not advertised as being such, so no real issue for me if I know that when I pick my shot.
A 2900-3000fps impact can put a lot of stress on nearly any cup/core bullet.
