So you have avoided real world shots because of bc differences, or due to bullet construction differences? If so, I'd be interested in reading about the circumstances.
Two examples where I avoided a shot: A monster blacktail in thick cover that saw me first and the only opportunity for a shot was a Texas heart shot before he disappeared. Didn't take the shot which I otherwise may have, if I had Barnes TSX loaded. Never saw him again. Another instance was on an overseas hunt high in the mountains of NZ after chamois. Avoided a 410 yard shot because of wind. Decided to stalk around the back of the mountain for a close shot. He was gone when I got to within 150 yards...never to be seen again. There are other instances as well such as an 850 yard shot that I had to empty the magazine before he was completely dead - the Bergers were accurate and had good terminal performance, but their bc wasn't very high and were getting blown around, together with shooter error. I don't shoot over 600 yards now (except for a 605 yard shot).