Last spring I went on a ground squirrel safari with a good friend who has access to very rich dirt rat hunting grounds..
Like most ranchers/farmers in Central California, he's always considered shooting dirt rats with anything other than a .22 LR as silly. I brought along a .223 squirrel sniper shooting hot 50 gr. BT's, a .22 mag shooting 30 gr. winchester supreme hollowpoints and a .17 HMR shooting hornady 17 gr. vmax's. I let him shoot them all, from "at your feet" to "dude, I can't see that far" ranges.
At the end of the day I had to pry the .22 mag out of his hands.