DigitalDan,
I see some higher BC's for .22 Magnum bullets, but they are not started at anywhere near the velocity of the .17 HMR bullets.
Having shot a lot of different .22 Magnum and .17 HMR rounds at various small rodents in the field, here in windy Montana, I have found the .17 HMR to be noticeably less affected by wind. Perhaps this is partly because on a typical summer day of 80-90 degrees (typical for ground squirrel shooting) the 2550 muzzle velocity of the .17 increases to 2600-2750 fps.