I've shot 2 big deer in the past 20 years in NE, both under 100 yards with a 25 WSSM, 110 grain AB, and a 260, 129 grain Hornady SpirePoint. Both were shot through the lungs, behind the shoulder. The deer shot with the 260 went, maybe, 20 yards before piling up and the deer shot with the 25 WSSM fell over dead in its tracks.

No air breathing animal can go far if you Wreck their lungs and since deer aren't usually dangerous, I don't see any reason to break bones if the target offers you a lung shot.

JEff