Stone, the old 06 with 150's shot in 3" high at 100 will be a bit low at 300, not much, but some as I remember.. A good bi pod will be a big help in open country also.. I ALWAYS have one on my rifles..
I think if you can find an accurate load for your 06, you will be surprised how you can hit at 300.. Just squeeze, and let your rifle do it..