I was the guy who had a 458 Win. Mag. that went haywire, then I used my 300 Win. Mag. for two Cape buffalo, as well as a lion.
I would certainly agree with Ray that a 270 Win. would serve as a very poor backup rifle for DG larger than leopard in case the big-bore went south during the course of a safari.
Tempting it is to go with the 270/375 combo, but at this stage of the game, I'm going with the 338/416 setup for this safari, and a big part of that decision is so that my hunting partner and I can both count on reserve ammo in the same calibers.
I also think that the 338/416 combo is a more sensible all-around tandem, at least for this particular safari..........
AD
Wonderful. I'd use the 300 win mag/416 rem mag combo today.