If shooting factory only I'd look hard at the federal fusion, I believe the 55 grain bullet is used in that offering.
I haven't used that bullet in 22-250 but have in the 223 and it's been impressive.
Also if you can get 55 grain hornady soft points they work great on broadside shots.
If you ever question a fast 22 cals killing ability on big game, go through scenarshooter's old posts and see the game he has killed with a 220 swift and standard cup and core bullets
