My daughter shot her first deer with a 22-250, a Ruger Flat Bolt that has been in the family since '70 or so. The shot was a quartering shot with the deer facing slightly toward her. It broke the large joint in the front shoulder, took out a few inches of scapula, went through the deer length-wise, broke a rear leg bone on the opposite side and "over-penetrated' leaving a 3/4" or so exit. I would say it works just fine, but we were using a good bullet--in this case a Nosler Bonded Solid Base. I've also shot a few large hogs with the same load with excellent results.I would have no problem shooting a cow elk with this Nosler load in a 22-250 if legal, broadside and the range wasn't too far. It's got the expansion and penetration to do the job.
