I can see no reason to push any weight bullet in the .405 Win to 2200fps, it simply is not needed. The .405 is much less of a round than the old .45-70 which isn't much to begin with anyway. The .405 loaded at moderate speeds will suffice as a small bear and marginal elk size animal round but it will never be more than that. Even "Old Bully" himself admited to it not being much of a DG round.
