Problem with the 10mm is bullet selection. The various 180-200gr JHP's are too lightly constructed for anything but lung shots on deer. Which is fine if you can work within its limitations. The heaviest loads consisting of 220-230gr LBT's at 1100fps are at best similar to middle weight loads for the .41 and .44 magnums. You can beat that in a Colt SAA .41Spl. If you're going to compare boutique loads, then it's best to look at Buffalo Bore's 230gr .41 load that runs 1450fps, or their 265gr load that runs 1350fps. No, the 10mm is not nipping at the heels of the .41Mag. It's not even close.