Problem with the 10mm is bullet selection. The various 180-200gr JHP's are too lightly constructed for anything but lung shots on deer. Which is fine if you can work within its limitations. The heaviest loads consisting of 220-230gr LBT's at 1100fps are at best similar to middle weight loads for the .41 and .44 magnums. You can beat that in a Colt SAA .41Spl. If you're going to compare boutique loads, then it's best to look at Buffalo Bore's 230gr .41 load that runs 1450fps, or their 265gr load that runs 1350fps. No, the 10mm is not nipping at the heels of the .41Mag. It's not even close.
In my experience the 180 grain XTP hp holds up rather well at 1300+ fps. The Buffalo Bore 265 grain clocked about 1260 fps from my S&W M-57. The 230 grain in the high 1300 fps range. A 40 cal 220 grain flat point is a formidable load my most things in the lower 48 IMHO.
But a 255 grain hard cast at 1090 fps from a 45 Super is very potent as well with the larger diameter.
