I once saw a doe pronghorn go over 600 yards with a hole from an expanded .25-caliber 115-grain bullet through both lungs. How's that for going a long ways with a good hit?
I'd always go with the rule & not the exception.
I'm sure an elk somewhere had gone a long ways after a solid .375 H&H Mag hit. Would that exception make the .375 H&H a poor elk round?