Leave the varmints, women, and children out of the discussion.
It's the baseline,safe harbor, center of the ballistic universe in hand- carried, shoulder- fired BG rifles.Most cartridge development has centered around improving on it somehow while still approaching its performance with bullets heavier and lighter.
Even people prone to hating it,inclined to pets bigger and smaller,have to admit that, if dumped unceremoniously in a remote location where BG animals are hunted,anywhere on the planet,with a 30/06 and proper ammo,know there's not much they can't kill,and they will be successful,ballistic theory notwithstanding.
Only maybe for less than a double handful of BG animals world wide might it be prudent to bring something bigger.And it isn't ridiculously "too much" for the rest.
