One of my neighbors and shooting partners (Broz) lives on an elk ranch, where they shoot a few dozen elk every year. His pet elk rifle is the 300 WinMag with a 215 Berger at around 2950 fps or so.

He generally gets only one hole up close, massive tissue disruption.

Longer distances, past 500 yards give or take, he starts to see two holes.

Pretty good example of a particular combo that digs deeper at lower impact speeds (ala 308 Win velocities).

Like I mentioned already, bullet design is so different, each type needs to be taken into consideration regarding how it will perform at likely impact velocities based on MV, target distance, etc.