A badly placed .338WM bullet may be - may be - marginally more effective than a 100 gr. .243 bullet, but I wouldn't put money on it.
Please explain. That sounds interesting.
Speculation. I try not to do research in this area.
But I see I could have made my post clearer. I was speculatively comparing calibers with the SAME bad placement. Not a badly placed .338 vs a well placed .243.