Eskimoes shoot what ever they have, if the game gets away here is always another.
Bullet placement is important, but what you hit them with is equally important.
One of my older friends, now gone, was a guide in Alaska for both polar bear and brown bear. His favorite rifle was a .270 and at one time he said 130 Silvertips. I would prefer something else, but he did it for years.
Another old timer now gone shot a .300 H & H with 180 Rem factory loads. He killed a ton of the big bears.
