Back in 1972 or 73 after I first started reloading, I accidently loaded up too much IMR 4350 in my 300 Win. In my manual, I looked at the IMR 4831 max charge weight instead. Went about 4 grains over. Don`t remember the bullet weight.
Ouch! Got nailed with about a 1/4 circled bloody scope gash above the left eye and damaged the firing pin as well. My smith at the time got a good laugh.