79S,
I know more than one African PH who prefers his Cape buffalo clients to use 270-grain .375 TSX's rather than 300's, BECAUSE they tend to stop under the hide, while the 300's tend to exit. Buffalo usually live in herds, either a small herd with a few other bulls, or a bigger herd including cows and calves--and they're often in pretty thick cover, where not all of the other members of the herd can be seen. PH's prefer not to shoot two buffalo with one bullet.
