The 270 & it's ballistic & performance twin, the 280 Rem have been my go-to rifles for quite a while.
1st rifle I ever bought was a 270 & I've kilt more with that round than all else put together & I've never been without at least one; 3 are in the stable at the moment.
Went down all the popular magnum routes, sold them all save for one 338 & aside from dangerous game, the 270, 280 & more lately, 7-08, do nicely for all other game.
I've had 150 gr Partitions from a 270 completely penetrate a moose & elk drop like they were pole axed.................really can't ask for better performance.