Thing I haven’t seen mentioned here is the necessity for frangible Ammo when running a higher powered cartridge in these situations. Don’t want to find myself having mistakenly used a Sunday school student as a backstop on a bad guy.

As others have said a .380 (which is what I carry loaded w/ 95 GR Hornady Critical defense) is better than nothing.

In a medium- to large-sized congregation I’d rather have a bunch of individuals spread across the worship area with .380s than a few with 45s.