Texas Hill Country.
Deer, hogs, misc exotics.
Short action rifle in any cartridge with a reputable bullet will kill them all.
I use 260/308/7-08/6.5CM. The difference for me is the optic. If I’m hunting the big open spaces, I’ve got scope with 15-16x top end.
For tighter cover under 200 yards or in the trees, It’s a 2.5-10 or similar.