Man people can allow their preferences to leave logic to the wayside.

Pick a revolver that is built to handle the 44 mag, and it can handle the 45 colt modern pressures. In that gun if it is chambered in the 44 mag it will (depending on barrel length): Launch a 300 gr cast bullet 1200-1300 fps. If it's chambered in a 45 colt, it will launch a 330 gr bullet 1200-1300 fps.

Now if you are using an LFN bullet design, per Veral's specs as a 44 it will have a meplat 0.130" less than bore diameter or .30", if a 45 it will be 0.32" in diameter which is a 14% larger meplat for the 45

Yes a 44 WFN will be larger than a 45 LFN, but a 45 WFN will be larger than a 44 WFN. A WFN by definition has a meplat 0.09" smaller than bore diameter or 0.34" for the 44 and 0.36" for the 45 and a 12% advantage to the 45

The 45 is always bigger by definition and picking and choosing different bullet designs is silly at best.

Now, for all intents and purposes I doubt there is a significant difference int the field between either round. Both in a quality gun are capable of outstanding accuracy and have more than enough power for NA game. I find the 45 a bit more flexible, especially with the availability of dual chambered 45 acp/45 colt guns.