You can read numbers and come to the conclusion that the 280 is (somehow) minutely better by fractions of "something"..
That's assuming you can avoid falling into a coma during the analysis...but when it comes to killing animals you will never in a million years and a million animals, tell the difference.
While I do enjoy my 280's my true first love was the 308 when I bought my first hunting rifle in 1976. I recently put it back into service since 2009. I cannot discern any difference between the two.
By the way, in case you missed it, Jeremiah was a bullfrog.