physics is fine. given a steel composition,strength per thickness equasion, now add in the strength of 2 lugs locking into that steel, there is a giving point.
now steel is not all made equal, so some is weaker than others even from the same batch.
one may come apart at a certain pressure and another way take even more.
just like anything made.
look at vehicles, one may run forever, and another be a problem child.

there are standards and mathematical formulas to determine what is a safe pressure for a given steel and thickness, but only trial and error will tell what it can handle.
my 280ai, with a common recommended load of vv n165 blew primers and i couldn't use them again as the primers just fell out after reloading those 2 rounds.
2 was enough to tell me that this recommended load wasn't going to be safe in MY rifle. but why others ?

yes, physics, pressure, steel, conditions, tempt's, etc., all come into play on reloading.
but i, and many others, think rifles are as different as people.
they all have their own unique personalities.