Not in my experience.
Bergers do often kill elk quickly if they make it to the lungs or if shoulders are avoided, no doubt...but accubombs, partitions, grand slams, and many other non-monos have given me 50-75 yard death runs on lung and shoulder shot elk, relatively often.

It's normally not a big deal for them to run that far before dying, but that has been my experience with non-monos, at normal velocities. YMMV, and that's fine. Use what works and gives confidence.