I guess you could kill a deer with just about anything out there with perfect shot placement. You're going to be in SK for a few days time and weather/wind, shot angle, and distance will all play a part in your shot. Shoot something that will allow you to make the shot when it counts (something you're familiar with and good at shooting), and something that has the juice to get the job done from a multitude of angles and at a distance if need be. For me, the 300 RUM with 180 BT will do it at any distance I care to shoot and allow for a small margin of error if I should make a poor shot, etc. So bring a 22LR if you can find some ammo and you are willing to accept the limitations, otherwise, if it were my money going into the hunt, I would pack a rifle that will get it done in every situation I might run into.