I have shot north of 130 critters or so with barnes regular tsx not the tipped version. Have used many calibers. 3006, 300wsm, 2506, 270, 257 wby mag, 7 mag, 223, 7x57, 375 H&H, and I have not had a single failure or lost a single animal with shots ranging from 50 to 600 yards. I would say that is statistically relevant. Every since they put the grooves in them and annealed the copper a bit more they have been really accurate out of almost all of my rifles and the fouling has mostly gone away. I also have taken game with accubonds and swift sirocco and they worked well. For standard c and c bullets I have found if a rifle won't shoot the sierra game king it probably won't shoot anything well. YMMV
