I shoot the 105 hybrids in my 243. Although technically a " target bullet" it performs like other Berger hunting bullets. I have killed a boatload of deer, and coyotes, as well as a wolf of two, and an antelope. The bullets are very accurate, and generally kill really quickly due to the fact that all of the energy is transferred inside of the animal, as the bullet fragments in a large wound chanel. The downside for some is that a lot of times because of this, there is no exit hole. This may vary with the size of game, and the size of bullet used. Shoot a Texas whitetail doe with a 180 grain berger, and you may have an exit the size of a soccer ball. On an elk, probably not. Berger also cause a lot of tissue damage in their expansion. This helps in quick klls, but many hunters don't like all the blood shot and mess. Hope that helps.