420 yard first shot coyote, using a 6x Leupold atop a .25-06 with a 115 Nosler Ballistic Tip. No problem:
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Also have a 400 yard one-shot mule deer doe, same rifle, same 6x scope. No problem.

My son took a good bear with the old .30-06, 6x Leupold, 320 yards. No problem. Only a few days after smacking his targets at the range, 100, 200 & 300 yards.

Really, the 6x is an excellent general purpose hunting scope. I like it to about 400 yards or so, maybe a little farther.

Regards, Guy