Lose a friend, job/career, kid or wife...............any of those alone, or in combination..............the emotional and financial costs can be huge.
Even a sane person making it through all that crap, can see the writing on the wall.

Only have so much time and money.

Some play congress and kick the can down the road.
Others draw a line and when it's hit............check out.

Not everybody thinks the same way. And just because somebody thinks differently, that doesn't mean they're F'd up or depressed.