Off the top of my head can think of 14 species of big game my wife and I have taken with the .30-06, pronghorns, whitetails, mule deer, caribou, bighorn sheep, black bear, elk, gemsbok, red hartebeest, kudu, blue wildebeest, red stag, feral goats and pigs, and no doubt some I've forgotten. Among mine were one of my biggest caribou at 450 yards, one of my biggest mule deer at almost 400, and my biggest bull elk at 250.
Now, we have taken quite a bit of other big game with dozens of cartridges ranging from the .22-250 up, but there isn't one I can think of that wouldn't have died pretty quickly when shot in the same place with a boring old 180-grain bullet from the .30-06, and that includes Cape buffalo.
As with boring old fixed-power scope, rifle loonies these days often think nit-picky details about cartridges, rifles and scopes make far more difference than they actually do. What does make a big difference is good bullets put in the right place.
I stopped reading right here.^^^. John's post sums it up perfectly. Thank you.
