I'd probably use my Brno 21h 7x64. Or maybe my Sako carbine in 30-06. And I'd limit my shots to less than 300 yds. Anything farther than that is just shooting, not hunting - to me anyway.
About angle - I don't shoot at animals going away from me any more. And I seldom shoot at animals facing directly towards me - unless I'm very, very sure of the shot.
Interesting how the presence of "Really BIG" animals often makes people forget basic principles - like making sure of a clean kill. With enough technology a "hunter" can overcome just about any limitation. To me hunting is more about hunting skills than shooting technology.
So, I'd call 'em in close and shoot 'em where it counts. Flame away!

Last edited by castnblast; 12/08/10.