Haven't ever owned a .380, but I've used and carried a 9 Mak for 20 years or so as my truck gun. The Mak is a .380 +P of a sort, shooting a slightly heavier bullet at a bit more speed - but not much. I've used it to put down a road-injured deer, and had it penetrate the skull completely.
The old saw that these little guns aren't much, but nobody ever volunteered to prove it as the target is true.