Just for the sake of numbers, let's assume a 4" spinal column. A hit would be the diameter of the spine plus twice the bullet diameter. A .45 cal adds almost an inch of dia, vs a 6.5 which would only add ~ 1/2 inch (ignoring wound channel width). The larger caliber has a greater chance of wrecking something vital, by odds alone. IMHO, of course.
Last edited by mark shubert; 08/08/17.
I've always been a curmudgeon - now I'm an old curmudgeon. ~Molɔ̀ːn Labé Skýla~
