You guys are the red herring kings. For police shootings of humans there is no discernible difference in 45, 40, 9mm as long as penetration is 13 inches or more. Also killing deer with a 223 and 62 grain TSX bullets is no different than killing them with a 308 and 150 grain bullets. Also I have killed over 100 deer in my life from little ones to way big ones. We are not shooting animals with handguns in this discussion.